Ezetimibe
Purpose of use of ezetimibe tablets
Athletes of all categories are subjected to high physical loads, due to which the strength and stability of cell membranes are significantly reduced. Therefore, ezetimibe tablets occupy an important place in the medicine cabinet of the athlete.
What is ezetimibe - this is a drug of the hypolipidemic class, which helps in the fight against excessive amounts of bad cholesterol.
So what are ezetimibe tablets for in people involved in sports activities? Taking the drug to athletes is necessary to normalize cholesterol levels, as it plays an important role in the production of hormones and bile, thanks to which there is a regulated synthesis of protein and energy metabolism.
Our data show that bodybuilders, representatives of iron sports, track and field athletes have accelerated metabolic process due to increased physical activity. In this regard, their body needs a balanced diet and more frequent meals. This nutritional mechanism provokes excessive accumulation of cholesterol and its transformation into "bad" cholesterol, and following a low-calorie diet helps to reduce its amount. Therefore, athletes leave positive ezetimibe reviews and advise to buy Ezetimibe, as the drug helps to keep to the golden mean in the amount of organic waxy substances.
Mechanism of action of Ezetimibe
Cholesterol is a fat-like substance that is produced by the cells of the liver, small intestine, adrenal cortex. Cholesterol belongs to the compounds that are independently produced in the body by 75-85%, the rest of the amount comes with food. This substance is indispensable, since with its help cells of all systems are built. It takes part in the creation of membranes and outer membranes of the cell. It is also necessary for the production of hormones such as testosterone and estrogen. At the same time, cholesterol is responsible for the formation of quality bile, which transforms fats and promotes their full digestion. Due to the correct formation and distribution of cholesterol, there is a qualitative formation of myelin sheaths of nerve fibers. But when the production is disturbed or excessive intake in the body, the formation of cholesterol plaques is observed, which lead to various cardiovascular diseases, narrowing of arteries, kidney dysfunction and aneurysm. This consequence is the main answer to the questions why should ezetimibe be ordered and what is ezetimibe used for?
Ezetimibe mechanism of action is to prevent the absorption of cholesterol through the intestine. The stages of action of the drug on the body:
- substantiation in the small intestine in the brush border;
- preventing the absorption of cholesterol that comes with food;
- reducing the amount of fat-like compounds in the liver;
- removal of excess through the bloodstream.
The principle of action of the drug allows you to maintain a normal amount of bile acid secretion, which prevents the inhibition of cholesterol by liver cells. Due to the low bioavailability, the drug binds to proteins by 99% and provides a high result of its work.
Application and dosage of Ezetimibe
The reception of the drug is recommended to begin with a preliminary full medical examination, taking a clinical and biochemical blood test. After the results obtained, it is mandatory to consult with the attending physician, who will draw up an individualized scheme of reception.
Before starting the course, it is necessary to follow a standard lipid-lowering diet for several weeks.
The drug is intended for oral administration. Acceptance of the drug does not depend on the time of day and meal period.
Order Ezetimibe should be calculated for the entire course.
The daily dosage of ezetimibe is 10 mg (1 tablet). Features of ezetimibe application:
- the drug is allowed to be combined with statins - the dose of the medication should not exceed the daily norm, the dosage of statins on the combo-course should be slightly higher (gram dosage is determined by the attending doctor);
- combination with bile acid sequestrants - the use of ezetimibe should occur 2 hours before taking BCA or after 4 hours after the use of bile acid sequestrants.
Elderly people and those suffering from renal/hepatic insufficiency do not need dosage adjustment, as ezetimibe side effects are not apparent for them. Ezetimibe use for children aged 6 to 17 years should be strictly under the supervision of a physician, as the efficacy and safety for this age group has not been established.
Ezetimibe side effects
The drug contains actively active components that, when interacting with the body, cause minor adverse reactions. Negative reactions have a minor character and short-term effect, but ezetimibe buy only after a detailed study of the instructions. In cases of overdose, the drug does not cause significant deterioration of the condition and other adverse reactions. Side effects of ezetimibe:
- decreased appetite, digestive upset, bloating, underlying nausea, abdominal cramps;
- fatigue not caused by physical exertion;
- headache, dizziness;
- false tingling in the upper and lower extremities;
- muscle pain of unclear etiology;
- swelling;
- cough, shortness of breath;
- allergic rashes, hives, itching;
- destruction of liver cells (ALT/AST increase).
Side effects of ezetimibe can significantly increase and cause irreversible processes in the body in the presence of hypersensitivity to the main components of the drug. Taking the drug together with fibrates can cause complications in the course of chronic diseases. Also, the use of the drug can provoke the transition of hepatic insufficiency from medium to severe. It is not recommended to take pregnant and lactating women, despite the acceptable cost of ezetimibe, because the use of ezetimibe can provoke disorders during organogenesis.
Ezetimibe cost online
Order the drug of the hypolipidemic class is possible in our specialized pharmacological online store. On the pages of the company's website there is a high-quality ezetimibe, the price of which has acceptable values. The quality of the drug is confirmed by certificates of originality and compliance. Highly qualified managers of the company help to select the necessary drugs according to the individual needs of the body.
